李亚敏，护理学博士后
湘雅二医院，教授，主任护师
学术型博士生导师
学术型硕士生导师/专业型硕士生导师
研究方向：精神卫生与心理护理/精神心理健康护理学/精神心理护理
教育背景
2013年-2015年：中南大学湘雅护理学院 护理学 博士后
2008年-2012年：中南大学湘雅二医院 精神卫生学 博士
2004年-2006年：中南大学公共卫生学院 社会医学 硕士
2002年-2004年：中南大学湘雅护理学院 护理学 本科
工作经历
2019年至今： 中南大学湘雅二医院 护理部 主任
2015年-2019年： 中南大学湘雅二医院 护理学教研室 副主任
2000年-2015年： 中南大学湘雅二医院 急诊科 护士长
1994年-2000年： 中南大学湘雅二医院 急诊科 护士
讲授课程
2020年--至今 中南大学湘雅护理学院 《高级护理临床实践》 研究生
2020年--至今 中南大学湘雅护理学院 《急危重症护理学》 本科生
2015年--至今 中南大学湘雅护理学院 《护理管理》 本科生/研究生
研究方向
精神卫生与心理护理
奖励荣誉
湖南省优秀科技工作者 （2022年/2021年）
湖南省三八红旗手 （2022年）
全国护理学专家学术影响力百强排名第10名 （2021年）
中南大学湘雅二医院“优秀研究生导师” （2020年）
中南大学湘雅二医院“师德先进个人” （2019年）
科研项目
主持国家自然科学基金项目2项，湖南省自然科学基金项目2项，湖南省重点研发计划项目1项，湖南省科技厅科技计划项目1项，湖南省教育厅研究生改项目1项，中南大学研究生教改项目1项。
代表性成果：
一、论文
1以第一/通讯作者发表英文文章
[1] ZHANG H, LI Y, ZENG Y, et al. Endothelin-1 Downregulates Angiotensin-Converting Enzyme-2 Expression in Human Bronchial Epithelial Cells [J]. Pharmacology, 2013, 91(5-6): 297-304.
[2] LEI X-Y, XIAO L-M, LIU Y-N, et al. Prevalence of Depression among Chinese University Students: A Meta-Analysis [J]. Plos One, 2016, 11(4):
[3] LI Y-M, PENG J, LI L-Z. Coffee consumption associated with reduced risk of oral cancer: a meta-analysis [J]. Oral Surgery Oral Medicine Oral Pathology Oral Radiology, 2016, 121(4): 381-U150.
[4] SHEN Y, OU J, LIU M, et al. Altered plasma levels of chemokines in autism and their association with social behaviors [J]. Psychiatry Research, 2016, 244(300-305.
[5] ZENG Y-N, LI Y-M. Secondhand smoke exposure and mental health in adults: a meta-analysis of cross-sectional studies [J]. Social Psychiatry and Psychiatric Epidemiology, 2016, 51(9): 1339-1348.
[6] LI Y-J, LI Y-M, XIANG D-X. Supplement intervention associated with nutritional deficiencies in autism spectrum disorders: a systematic review [J]. European Journal of Nutrition, 2018, 57(7): 2571-2582.
[7] LI Y-M, SHEN Y-D, LI Y-J, et al. Maternal dietary patterns, supplements intake and autism spectrum disorders A preliminary case-control study [J]. Medicine, 2018, 97(52):
[8] LIAO X, LEI X, LI Y. Stigma among parents of children with autism: A literature review [J]. Asian Journal of Psychiatry, 2019, 45(88-94.
[9] ZENG Y, LIN R, LIU L, et al. Ambient air pollution exposure and risk of depression: A systematic review and meta-analysis of observational studies [J]. Psychiatry Research, 2019, 276(69-78.
[10] CHEN Q, LIANG M, LI Y, et al. Mental health care for medical staff in China during the COVID-19 outbreak [J]. Lancet Psychiatry, 2020, 7(4): E15-E16.
[11] CHEN R, WANG Y, LIU L, et al. A qualitative study of how self-harm starts and continues among Chinese adolescents [J]. Bjpsych Open, 2020, 7(1):
[12] FU X, YANG J, LIAO X, et al. Parents' Attitudes Toward and Experience of Non-Suicidal Self-Injury in Adolescents: A Qualitative Study [J]. Frontiers in Psychiatry, 2020, 11(
[13] LI Y-J, XIE X-N, LEI X, et al. Global prevalence of obesity, overweight and underweight in children, adolescents and adults with autism spectrum disorder, attention-deficit hyperactivity disorder: A systematic review and meta-analysis [J]. Obesity Reviews, 2020, 21(12):
[14] LIAO X, LI Y. Economic burdens on parents of children with autism: a literature review [J]. Cns Spectrums, 2020, 25(4): 468-474.
[15] LIAO X, LI Y. Genetic associations between voltage-gated calcium channels and autism spectrum disorder: a systematic review [J]. Molecular Brain, 2020, 13(1):
[16] LIAO X, LI Y. Nuclear Factor Kappa B in Autism Spectrum Disorder: A Systematic Review [J]. Pharmacological Research, 2020, 159(
[17] LIAO X, LIU Y, FU X, et al. Postmortem Studies of Neuroinflammation in Autism Spectrum Disorder: a Systematic Review [J]. Molecular Neurobiology, 2020, 57(8): 3424-3438.
[18] LIAO X, YANG J, WANG H, et al. Microglia mediated neuroinflammation in autism spectrum disorder [J]. Journal of Psychiatric Research, 2020, 130(167-176.
[19] LIU H, LI X, CHEN Q, et al. Illness perception, mood state and disease-related knowledge level of COVID-19 family clusters, Hunan, China [J]. Brain Behavior and Immunity, 2020, 88(30-31.
[20] TIAN Y, YUE Y, WANG J, et al. Workplace violence against hospital healthcare workers in China: a national WeChat-based survey [J]. Bmc Public Health, 2020, 20(1):
[21] YANG J, FU X, LIAO X, et al. Effects of gut microbial-based treatments on gut microbiota, behavioral symptoms, and gastrointestinal symptoms in children with autism spectrum disorder: A systematic review [J]. Psychiatry Research, 2020, 293(
[22] YANG J, FU X, LIAO X, et al. Nrf2 Activators as Dietary Phytochemicals Against Oxidative Stress, Inflammation, and Mitochondrial Dysfunction in Autism Spectrum Disorders: A Systematic Review [J]. Frontiers in Psychiatry, 2020, 11(
[23] YANG J, FU X, LIAO X, et al. Association of problematic smartphone use with poor sleep quality, depression, and anxiety: A systematic review and meta-analysis [J]. Psychiatry Research, 2020, 284(
[24] YANG J, HU H, LI Y. EFFECT OF DUAL-TRACK INTERACTIVE NURSING INTERVENTION MODEL ON ANXIETY AND DEPRESSION IN PATIENTS WITH CORONARY HEART DISEASE [J]. Psychiatria Danubina, 2020, 32(2): 197-204.
[25] CHEN H, LI Y, WANG W, et al. Reliability and validity of the multidimensional dyspnea profile in hospitalized Chinese patients with respiratory diseases [J]. SAGE open medicine, 2021, 9(2050312120965336-2050312120965336.
[26] FU X, YANG J, LIAO X, et al. Parents' and medical staff's experience of adolescents with suicide-related behaviors admitted to a general hospital in China: qualitative study [J]. Bmc Psychiatry, 2021, 21(1):
[27] HE Q, LI Y, ZHOU X, et al. The combination of fibrinogen concentrations and the platelet-to-lymphocyte ratio predicts survival in patients with advanced lung adenocarcinoma treated with EGFR-TKIs [J]. Journal of International Medical Research, 2021, 49(4):
[28] LI S, LI J, PENG L, et al. Cost-Effectiveness of Frontline Treatment for Advanced Renal Cell Carcinoma in the Era of Immunotherapies [J]. Frontiers in Pharmacology, 2021, 12(
[29] LI S, LI J, PENG L, et al. Cost-Effectiveness of Lorlatinib as a First-Line Therapy for Untreated Advanced Anaplastic Lymphoma Kinase-Positive Non-Small Cell Lung Cancer [J]. Frontiers in Oncology, 2021, 11(
[30] LI S, LI J, PENG L, et al. Cost-effectiveness of Triple Therapy vs. Biologic Treatment Sequence as First-line Therapy for Rheumatoid Arthritis Patients after Methotrexate Failure [J]. Rheumatology and Therapy, 2021, 8(2): 775-791.
[31] LI S, LI J, PENG L, et al. Cost-Effectiveness of Baricitinib for Patients with Moderate-to-Severe Rheumatoid Arthritis After Methotrexate Failed in China [J]. Rheumatology and Therapy, 2021, 8(2): 863-876.
[32] LI S, LI J, PENG L, et al. Cost-Effectiveness of Nivolumab Plus Cabozantinib Versus Sunitinib as a First-Line Treatment for Advanced Renal Cell Carcinoma in the United States [J]. Frontiers in Pharmacology, 2021, 12(
[33] LI S, LI J, PENG L, et al. First-line Daratumumab in Addition to Chemotherapy for Newly Diagnosed Multiple Myeloma Patients Who are Transplant Ineligible: A Cost-Effectiveness Analysis [J]. Clinical Therapeutics, 2021, 43(7): 1253-+.
[34] LIANG M, LI Y, CHEN Q, et al. The Difficulties and Mental Health Intervention Need of Doctors and Nurses in Biological Emergencies: A Qualitative Study [J]. Frontiers in Psychiatry, 2021, 12(
[35] LIU R, DONG H, WANG Y, et al. Sleep Problems of Children with Autism May Independently Affect Parental Quality of Life [J]. Child Psychiatry & Human Development, 2021, 52(3): 488-499.
[36] SHEN Y, LI Y, SHI L, et al. Autism spectrum disorder and severe social impairment associated with elevated plasma interleukin-8 [J]. Pediatric Research, 2021, 89(3): 591-597.
[37] TIAN Y, YUE Y, LIAO X, et al. Mental health service use and its associated factors among nurses in China: a cross-sectional survey [J]. Peerj, 2021, 9(
[38] WANG H, DENG S, FAN X, et al. Research Trends and Hotspots of Extracorporeal Membrane Oxygenation: A 10-Year Bibliometric Study and Visualization Analysis [J]. Frontiers in Medicine, 2021, 8(
[39] WANG L, NORMAN I, XIAO T, et al. Psychological First Aid Training: A Scoping Review of Its Application, Outcomes and Implementation [J]. International Journal of Environmental Research and Public Health, 2021, 18(9):
[40] WANG Y, LIN J, ZENG Y, et al. Effects of Sleep Disturbances on Behavioral Problems in Preschool Children With Autism Spectrum Disorder [J]. Frontiers in Psychiatry, 2021, 11(
[41] YANG Y, LIN J, LU X, et al. Anesthesia, sex and miscarriage history may influence the association between cesarean delivery and autism spectrum disorder [J]. Bmc Pediatrics, 2021, 21(1):
[42] ZHAI M, LONG J, LIU S, et al. The burden of liver cirrhosis and underlying etiologies: results from the global burden of disease study 2017 [J]. Aging-Us, 2021, 13(1): 279-300.
[43] ZHAI M, ZHANG D, LONG J, et al. The global burden of thyroid cancer and its attributable risk factor in 195 countries and territories: A systematic analysis for the Global Burden of Disease Study [J]. Cancer Medicine, 2021, 10(13): 4542-4554.
[44] CHEN Z, PENG K, LIU X, et al. Association between high burn-out and workplace violence among healthcare workers in China: a WeChat-based survey [J]. Bmj Open, 2022, 12(11):
[45] DENG C, XIE Y, LIU Y, et al. Aromatherapy Plus Music Therapy Improve Pain Intensity and Anxiety Scores in Patients With Breast Cancer During Perioperative Periods: A Randomized Controlled Trial [J]. Clinical Breast Cancer, 2022, 22(2): 115-120.
[46] HUANG S, LIAO X, WU J, et al. The Microglial membrane receptor TREM2 mediates exosome secretion to promote phagocytosis of amyloid-beta by microglia [J]. Febs Letters, 2022, 596(8): 1059-1071.
[47] LI Y, LIU Y, ZHANG L, et al. Acupuncture for Pain and Function in Patients with Nonspecific Low Back Pain: Study Protocol for an Up-to-Date Systematic Review and Meta-Analysis [J]. Journal of Pain Research, 2022, 15(1379-1387.
[48] LI Z, LI J, LI Y, et al. Anxiety and depression in the post-pandemic era: concerns about viral mutation and re-outbreak [J]. Bmc Psychiatry, 2022, 22(1):
[49] OU J, SMITH R C, TOBE R H, et al. Efficacy of Sulforaphane in Treatment of Children with Autism Spectrum Disorder: A Randomized Double-Blind Placebo-Controlled Multi-center Trial [J]. Journal of Autism and Developmental Disorders, 2022,
[50] TIAN Y, YUE Y, YANG J, et al. Sociodemographic, occupational, and personal factors associated with sleep quality among Chinese medical staff: A web-based cross-sectional study [J]. Frontiers in Public Health, 2022, 10(
[51] WANG L, NORMAN I, XIAO T, et al. Evaluating a Psychological First Aid Training Intervention (Preparing Me) to Support the Mental Health and Wellbeing of Chinese Healthcare Workers During Healthcare Emergencies: Protocol for a Randomized Controlled Feasibility Trial [J]. Frontiers in Psychiatry, 2022, 12(
[52] XIAO Y, LI Y, CAI Z, et al. Investigation on the Correlation of Anxiety Degree with Family Atmosphere in Children with Precocious Puberty [J]. Emergency Medicine International, 2022, 2022(
[53] XIE C, LI L, LI Y. Learned Helplessness in Renal Dialysis Patients: Concept Analysis with an Evolutionary Approach [J]. Patient Preference and Adherence, 2022, 16(2301-2312.
[54] YANG J, CHEN Y, YAO G, et al. Key factors selection on adolescents with non-suicidal self-injury: A support vector machine based approach [J]. Frontiers in Public Health, 2022, 10(
[55] YANG Y, SHEN Y, LIN J, et al. Association between history of miscarriage and autism spectrum disorder [J]. European Archives of Psychiatry and Clinical Neuroscience, 2022,
[56] YE M, CHEN S-H, LI X-T, et al. Effects of Disease-Related Knowledge on Illness Perception and Psychological Status of Patients With COVID-19 in Hunan, China [J]. Disaster Medicine and Public Health Preparedness, 2022, 16(4): 1415-1422.
[57] ZHAI M, JIANG Q, LIU S, et al. DALY trend and predictive analysis of COPD in China and its provinces: Findings from the global burden of disease study [J]. Frontiers in Public Health, 2022, 10(
[58] ZHANG C, SHI L, TIAN T, et al. Associations Between Academic Stress and Depressive Symptoms Mediated by Anxiety Symptoms and Hopelessness Among Chinese College Students [J]. Psychology Research and Behavior Management, 2022, 15(547-556.
[59] LI L, LU S, XIE C, et al. Stigmatizing attitudes toward mental disorders among non-mental health nurses in general hospitals of China: a national survey [J]. Frontiers in Psychiatry, 2023, 14(
[60] LI L, XIE C, LI Y. Factors Associated with Self-Management of Peritoneal Dialysis Patients in Urumqi of Xinjiang of China: A Cross-Sectional Survey [J]. Patient Preference and Adherence, 2023, 17(1573-1589.
[61] LI S, CHEN Z, YONG Y, et al. Effectiveness of acceptance and commitment therapy-based interventions for improving the psychological health of parents of children with special health care needs: A systematic review and meta-analysis [J]. Comprehensive psychiatry, 2023, 127(152426-152426.
[62] LI S, YONG Y, LI Y, et al. Cognitive-Based Interventions for Improving Psychological Health and Well-Being for Parents of Children with Developmental Disabilities: A Systematic Review and Meta-analysis [J]. Journal of Autism and Developmental Disorders, 2023,
[63] LI W, LI X, CHEN T, et al. Factors affecting lung cancer patients' intention to perform early postoperative exercise: a qualitative study based on theory of planned behavior [J]. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2023, 31(12): 649-649.
[64] LI X, CHE C C, LI Y, et al. The mediating role of coping styles in the relationship between second victim experience and professional quality of life among nurses: a cross-sectional study [J]. Bmc Nursing, 2023, 22(1):
[65] LI X, LIU S, TIAN Y, et al. Challenges for psychiatric nurses working with non-suicidal self-injury adolescents: a qualitative study [J]. Bmc Nursing, 2023, 22(1):
[66] LIANG M, CHEN Q, GUO J, et al. Mental health first aid improves mental health literacy among college students: A meta-analysis [J]. Journal of American College Health, 2023, 71(4): 1196-1205.
[67] LIAO X, CHEN M, LI Y. The glial perspective of autism spectrum disorder convergent evidence from postmortem brain and PET studies [J]. Frontiers in Neuroendocrinology, 2023, 70(
[68] LONG Y, WANG Y, SHEN Y, et al. Minocycline and antipsychotics inhibit inflammatory responses in BV-2 microglia activated by LPS via regulating the MAPKs/ JAK-STAT signaling pathway [J]. Bmc Psychiatry, 2023, 23(1):
[69] XIE C, LI L, LI Y. Trajectories of Learned Helplessness in Maintenance Haemodialysis Patients and Their Predictive Effects on Self-Management: A Latent Growth Mixture Modeling Approach [J]. Psychology Research and Behavior Management, 2023, 16(351-361.
[70] XIE C, LI L, LI Y. Humor-based interventions for patients undergoing hemodialysis: A scoping review [J]. Patient Education and Counseling, 2023, 114(
[71] XIE C, LI L, LI Y. "Alive Day is the Day": A Qualitative Study of Experiences of Learned Helplessness in Maintenance Haemodialysis Patients [J]. Risk Management and Healthcare Policy, 2023, 16(231-245.
[72] XIE C, LI L, ZHOU L, et al. Mediating role of learned helplessness' components in the association between health literacy/social support and self-management among maintenance haemodialysis patients in Changsha, China: a cross-sectional study [J]. Bmj Open, 2023, 13(8):
[73] XIE C, ZHOU L, SUN C, et al. The cross-cultural adaptation and psychometric evaluation of a learned helplessness scale for maintenance hemodialysis patients in China (LHS-MHD-C) [J]. Research in Nursing & Health, 2023, 46(2): 251-262.
[74] XIE J, LI S, LI Y, et al. Cost-effectiveness of sacituzumab govitecan versus chemotherapy in patients with relapsed or refractory metastatic triple-negative breast cancer [J]. Bmc Health Services Research, 2023, 23(1):
[75] YANG J, SHEN Y, TIAN Y, et al. Investigating and comparing the psychometric properties of the Chinese Mandarin version of social responsiveness scale-2 and its shortened version in preschool-age children with autism spectrum disorder [J]. Asian Journal of Psychiatry, 2023, 79(
[76] YU Q, WANG H, TIAN Y, et al. Moral courage, job-esteem, and social responsibility in disaster relief nurses [J]. Nursing Ethics, 2023,
[77] ZHAI M, LI Y, LI Y. Choice of evaluation time points and improvement of web-based transitional care programme [J]. Journal of Clinical Nursing, 2023, 32(15-16): 5396-5397.
2以第一/通讯作者发表中文文章（CSCD&CSSCI）
[1] 成年女性FSH水平与骨密度和骨质疏松患病率的关系 [J]. 中南大学学报(医学版), 2009, 34(08): 803-806.
[2] 心肺复苏中基础及进一步生命支持阶段优化实施的探讨 [J]. 第三军医大学学报, 2010, 32(17): 1883-1886.
[3] 无精神疾病自杀未遂者个性特征及社会支持状况研究 [J]. 中国临床心理学杂志, 2010, 18(02): 194-195.
[4] 中国大学生自杀意念影响因素的元分析 [J]. 中国临床心理学杂志, 2014, 22(04): 638-640+667.
[5] 认知矫正治疗对精神分裂症患者认知功能和服药依从性的影响 [J]. 第三军医大学学报, 2015, 37(16): 1682-1684.
[6] 他汀类药物对癌症患者预后的Meta分析 [J]. 中南大学学报(医学版), 2015, 40(07): 770-781.
[7] 社会支持对精神分裂症患者生活质量和康复的影响 [J]. 中国临床心理学杂志, 2016, 24(01): 185-187.
[8] 腺苷酸活化蛋白激酶与脓毒症心功能不全的研究进展 [J]. 中南大学学报(医学版), 2018, 43(12): 1364-1368.
[9] 孤独症谱系障碍儿童家庭复原力现状及影响因素分析 [J]. 中国临床心理学杂志, 2019, 27(06): 1271-1274.
[10] 儿童孤独症谱系障碍药物治疗的研究现状 [J]. 中国临床药理学杂志, 2019, 35(24): 3261-3264.
[11] ICU机械通气患者早期康复训练研究进展 [J]. 中国康复医学杂志, 2019, 34(05): 617-619.
[12] 付晚期慢性阻塞性肺疾病患者姑息照护的研究进展 [J]. 中华护理杂志, 2020, 55(09): 1426-1431.
[13] 儿童重症监护病房和新生儿重症监护病房死亡患儿父母心理干预研究进展 [J]. 解放军护理杂志, 2020, 37(03): 61-64.
[14] 医护人员对ICU日记认知和态度的质性研究 [J]. 解放军护理杂志, 2020, 37(05): 49-52.
[15] ICU丧亲者心理支持研究进展 [J]. 护理学杂志, 2020, 35(04): 101-104.
[16] 邓护士组织氛围感知对第二受害者经历与支持的影响 [J]. 解放军护理杂志, 2020, 37(10): 1-4.
[17] 邓洁, 刘义婷, 李亚敏. 精神分裂症患者病耻感的研究进展 [J]. 解放军护理杂志, 2020, 37(04): 75-77.
[18] 医院即将退休护士执业发展研究进展 [J]. 护理学杂志, 2020, 35(19): 110-112.
[19] 心理健康急救：一项有效的公共卫生干预 [J]. 中国临床心理学杂志, 2021, 29(01): 209-213.
[20] 护理专业实习生在思政育人临床实践教学中的体验 [J]. 中华护理教育, 2021, 18(11): 994-999.
[21]常态化疫情防控机制下综合医院探视陪护管理 [J]. 护理学杂志, 2021, 36(12): 62-65.
[22] 青年HIV/AIDS患者心理痛苦多维现状及其影响因素分析 [J]. 中国艾滋病性病, 2023, 29(10): 1114-1119.
[23] 心理痛苦耐受性量表的汉化及在青年HIV感染者/AIDS患者中的信效度检验 [J]. 中华护理杂志, 2023, 58(07): 891-897.
[24] 青少年非自杀性自伤影响因素的研究进展 [J]. 中国临床心理学杂志, 2023, 31(05): 1145-1149.
[25] 个体及家庭因素对情绪障碍青少年非自杀性自伤行为的影响. 中华精神科杂志，2023，56(04):276-283.
二、专利
1. 发明专利：一种急诊科护理用品快速预清洁装置
2. 实用新型专利：一种医用可调式移动输液泵架
3. 实用新型专利：一种盛装止血器的盒子
4. 实用新型专利：一种卡带式经口气管导管固定装置
5. 实用新型专利：一种棉签盒
6. 实用新型专利：一种多功能收纳盒
三、著作
1主编教材
1.护理学专业融媒体教材《急救护理学》 主 编 2023 中南大学出版社
2.《专科技能培训教程-护理学分册》 主 编 2023 人民卫生出版社
3.《急危重症护理情景模拟案例训练手册》 主 编 2023 人民卫生出版社
4.国家卫健委十四五规划教材《护理心理学》 副主编 2022 人民卫生出版社
5.湖南省专科护理培训教材《急诊专科护理》 主 编 2018 人民卫生出版社
6.教育护理学十三五规划教材《护理学导论》 副主编 2017 中南大学出版社
2学术专著
1.《新冠肺炎疫情防控应急护理手册》 主 编 2020 湖南科学技术出版社
2.《新型冠状病毒肺炎大众防护与心理疏导》 副主编 2020 中南大学出版社
3.《急危救治护士临床工作手册》 副主编 2018 湖南科学技术出版社
4.湖南省专科护士培训丛书《急诊专科护理 》 副主编 2010 湖南科学技术出版社
5.《专科护士培训丛书-急诊专科护理分册》 主 编 2009 湖南科学技术出版社
学术兼职（不超过5项）
中华护理学会精神卫生护理专业委员会 副主任委员
中国医学救援协会心理救援分会 常务理事
中国研究型医院护理学研究分会 常务理事
湖南省护理学会心理护理专委会 主任委员
《中华护理杂志》 编 委
《中国护理管理》杂志 编 委
《湘雅护理杂志》 主 编
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