唐四元,临床医学博士后

湘雅护理学院,二级教授,国务院政府特殊津贴专家

博士研究生和博士后导师

学术型硕士生导师

中南大学湘雅护理学院原院长

研究方向:社区慢性病预防与管理

教育背景

2009-2010 美国犹他大学基础医学博士后

2006-2008 中南大学临床医学博士后

2003-2006 中南大学基础医学生理学博士

2000-2003中南大学基础医学病理学硕士

1994-1996 教育部本科师资基础医学学士

工作经历

2013-2023 中南大学湘雅护理学院院长

2010-2013 中南大学湘雅护理学院党委书记

2005-2010 中南大学湘雅护理学院副院长

2013-至今 获评国家二级教授,2018年获评国务院政府特殊津帖专家

2008-2013 中南大学教授

2003-2008 中南大学副教授讲授课程(请替换以下内容,填写在中南大学湘雅护理学院主要授课课程,注明本科或者研究生课程)

奖励荣誉

(1)2023年获世界前2% 顶极科学家(World top 2% scientists)

(2)2022年获高等教育(研究生)国家级教学成果奖二等奖

(3)2021年全球学者库评审,获中国大陆护理学领域专家学术影响力百强排名第1位

(4)2021年获湖南省科技进步奖一等奖

(5)2019年获湖南省教学成果二等奖

(6)2018年享受国务院政府特殊津贴

(7)2018年获卢惠霖奖励金优秀教师奖

(8)2018年获中南大学导师·研究生科研团队优秀奖

(9)2018年获湖南省医学科技奖二等奖

(10)2016年主讲的《社区护理学》获批国家级精品资源共享课

(11)2015年获中华护理学会科技奖三等奖

(12)2014年主讲的《社区慢性病护理与管理》获批国家级精品视频公开课

(13)2014年《骨形成蛋白(BMP-2)在癌细胞代谢及凋亡中的作用模式与机制》获第十一届湖南医学科技奖三等奖

(14)2013年获评国家二级教授

(15)2013年《Apelin/APJ在骨重建过程中的作用模式与机制》

获湖南省自然科学奖二等奖

(16)2012年“以循证护理为切入点的护理本科生教学模式研究与改革”获中南大学教学成果一等奖

(17)2011年获宝钢教育奖

科研项目

(1)APJ在骨代谢调控中的作用模式与机制研究,国家自然科学基金,2008。

(2)Apelin-APJ对成骨/破骨细胞的作用模式及机理研究,2008年湖南省博士后科学基金1项。

(3)Apelin/apj抗软骨细胞凋亡在骨性关节炎中的作用及机制研究,2010年长沙市科技计划项目。

(4)网膜素-1通过调控OPG/RANKL表达拮抗血管钙化和骨质疏松的作用机制。2012年度高等学校博士学科点专项科研基金(博导类)。

(5)网膜素-1通过调控OPG/RANKL表达拮抗血管钙化和骨质疏松的作用机制。2012年长沙市科技计划项目。

(6)ER-α36介导淫羊藿素的骨保护作用,国家自然科学基金,2013。

(7)商务部一带一路护理项士项目,2015-2023。

(8)湖南省积极老龄化综合技术集成与示范,湖南省重点计划项目,2019

(9)医养结合视域下高龄老年女性社区养模式的构建湖南省妇联项目,2019

(10)横向课题:老年长期照护服务体系研究及支撑技术开发,2019。

(11)NMDA受体介导糖尿病胰岛β细胞去分化与转分化中的作用与机制研究,国家自然科学基金,2021。

(12)护理伦理专业人才培养模式探索,教育部新文科项目,2021。

(13)国家重点研发计划“主动健康和人口老龄化科技应对”重点专项子课题“面向医养康融合的智能化服务关键技术研究,2022。


代表性成果(论文、专利、著作):

1. Wang, J., Yu, X., Ren, L., & Tang, S*. Design and development of ICU intelligent medicine management system based on MVC. IEEE International Conference on Bioinformatics and Biomedicine.(2017). (pp.1023-1027). IEEE.(SCI)

2.Zhang H,Jin L,Mu T,Fan Y,Zhang H,Zhu Y,Mao X,Li R,Tang S*.Associations of CYP4A11 gene-gene and gene-smoking interactions with essential hypertension in the male eastern Chinese Han population.[J]. Clin Exp Hypertens, 2017.39(5):448-453.(SCI)

3.Zhang H,Sun J,Zhang H,Zhu Y,Xujie X M,Ai F, Tang S*,Li R. Correlation between compliance in patients with anti-hypertensive therapy and blood pressure control.[J].Pakistan Journal of Pharmaceutical Sciences: 2017.1455-1460.(SCI)

4. Wang Jingxia, Tang Si-Yuan*.Career Decision-Making Self-Efficacy and Professional Commitment Among Master Nursing Students.  2017.01

5.Ren, Y., Jiang, X., Tang, S*. 3d body software experimental platform for course of sports anatomy. International Journal of Emerging Technologies in Learning, (2017). 12(9), 4.(SCI)

6.Xiaofei Z,Hui F,Lawn S J,Mei S,Smith D,Jingxia W,Lu R,Jiarui C,Siyuan T*. Translation and initial psychometric evaluation of the Chinese version of the partners in health scale[J] 2017,28 (16)

7.Qin C,Mi C,Xia A,Chen W T,Chen C,Li Y,Li Y,Bai W,Tang S*.A first look at the effects of long inter-pregnancy interval and advanced maternal age on perinatal outcomes: A retrospective cohort study[J].Brirh, 2017.44(3):230-237(SCI)

8. Qin, Yue‐Lan, & Tang, Si‐Yuan*. Maternal pre‐pregnancy body mass index and autism spectrum disorder among offspring. Paediatric & Perinatal Epidemiology, (2017).31(2), 165.(SCI)

9. Zhang Huimin, Tang Si-Yuan*.Associations of CYP4A11 gene–gene and gene–smoking interactions with essential hypertension in the male eastern Chinese Han population.  2017(5)

10. Zhang Huimin, Tang Si-Yuan*.Correlation between compliance inpatient swithantihypertensive therapy and bloodpressure control. 2017(7)

11. Bai, X., Luo, Z., Lou, T., Pang, J., & Tang, S*. (2018). Career intentions of PhD students in nursing: a cross-sectional survey. Nurse Education Today, 64, 196. (Q1, IF:2.067)

12. Qin, C., Deng, Y., Chen, W. T., Mi, C., Wang, W., Sun, M., Chen, J., Liu, W., Tang, S*. (2018). Does previous cesarean section influence neonatal birth weight? a path analysis in china. Women & Birth Journal of the Australian College of Midwives. (Q1, IF: 1.822)

13. Qin, C., Li, Y., Wang, D., Shi, Z., Yao, R., Wang, D., Tang, S*. (2018). Maternal factors and preoperative nutrition in children with mild cases of congenital heart disease. Japan Journal of Nursing Science Jjns. (Q3, IF: 1.062)

14. Qin, Chunxiang,Tang Si-Yuan*.  (2018).Factors in Healthcare Violence in Care of Pregnancy Termination Cases: A Case Study. Plos One (IF: 2.766)

15. Xiao-Ting Huang, Wei Liu, Yong Zhou, Mei Sun, Chen-Chen Sun, Chen-Yu Zhang, Tang Si-Yuan*. Endoplasmic reticulum stress contributes to NMDA-induced pancreatic β-cell dysfunction in a CHOP-dependent manner. Life Sciences. 2019, 28:116612 (IF: 3.448)

16. Feng Ge, Minhui Liu,Siyuan Tang*, Yongjin Lu, Assessing Frailty in Chinese Nursing Home Older Adults: A Comparison Between the FRAIL-NH Scale and Frailty Index. Journal of Nutrition, Health, 2019, 23(3):291-298 (IF: 2.868)

17. Yin H, Chen CY, Liu YW, Tan YJ, Deng ZL, Yang F, Huang FY, Wen C, Rao SS, Luo MJ, Hu XK, Liu ZZ, Wang ZX, Cao J, Liu HM, Liu JH, Yue T, Tang Si-Yuan*, Xie H. Synechococcus elongatus PCC7942 secretes extracellular vesicles to accelerate cutaneous wound healing by promoting angiogenesis. Theranostics, 2019,9(9):2678-2693 (IF: 8.537)

18. Chunxiang Qin,Wei-Ti Chen,Yunlong Deng,Yao Li ,Chunmei Mi,Linli Sun, Tang Si-Yuan*. Cognition,emotion,and behaviour in women undergoing pregnancy termination for foetal anomaly: A grounded theory analysis. Midwifery, 2019,68:84-91 (IF: 2.453)

19. Zhao F#, Liu W#, Yue S, Yang L, Hua Q, Zhou Y, Cheng H, Luo Z*, Tang S*.Pretreatment with G-CSF Could Enhance the Antifibrotic Effect of BM-MSCs on Pulmonary Fibrosis. Stem Cells Int, 2019, 2019:1726743 (IF: 3.989)

20. Jiarui Chen ,Wendy M. Cross ,Virginia Plummer ,Louisa Lam , Chunxiang Qin,Mei Sun ,Siyuan Tang*. The risk factors of antenatal depression: A cross-sectional survey. Journal of clinical  nursing. 2019,:710-713 (IF: 1.757)

21. Xiaoling Bai,Anni Wang,Virginia Plummer,Louisa Lam,Wendy Cross,Ziyao Guan,Xin Hu,Mei Sun,Siyuan Tang*. Using the theory of planned behaviour to predict nurse's intention to    undertake dual practice in China: A multicentre survey. Journal of clinical  nursing. 2019,28(11-12):2101-2110 (IF: 1.757)

22. Chen, Jiarui; Cross, Wendy M; Plummer, Virginia; Lam, Louisa;Siyuan,Tang*.A systematic review of prevalence and risk factors of postpartum depression in Chineseimmigrant women. Women and birth. 2019,32(6):487-492(IF: 2.079)

23. Xiao-Ting Huang, Wei Liu, Yong Zhou, Cai-Xia Hao, Yan Zhou, Chen-Yu Zhang, Chen-Chen Sun, Zi-Qiang Luo, Si-Yuan Tang*. Dihydroartemisinin attenuates lipopolysaccharide‑induced acute lung injury in mice by suppressing NF‑κB signaling in an Nrf2‑dependent manner. international journal of molecular medicine. 2019;44(6):2213-2222(IF: 2.928)

24. Xiao-Ting Huang,Wei Liu, Yong Zhou, Mei Sun, Hui-Hui Yang, Chen-Yu Zhang, Si-Yuan Tang*. Galectin-1 ameliorates lipopolysaccharide-induced acute lung injury via AMPK-Nrf2 pathway in mice. free radical biology and medicine. (IF: 5.657)

25. Ziyao Guan, Chongmei Huang, James A. Wiley, Xiao long Bai, Mei Sun, Siyuan Tang*. Internalized stigma and its correlates among family caregivers of patients diagnosed with schizophrenia in Changsha, Hunan, China. Journal of psychiatric and mental health nursing. (IF: 2.009)

26. Qirong Chen, Mei Sun, Siyuan Tang*, Aimee R. Castro. Research capacity in nursing: a concept analysis based on a scoping review. BMJ Open. 2019,9(11):e032356. (IF: 2.376)

27. Ziyao Guan, Mei Sun, Siyuan Tang*.Feasibility of brief distress screening for family caregivers of adults diagnosed with schizophrenia in Changsha,Hunan,China. Journal of Psychiatric and mental health nursing, 202006 (IF: 1.947)

28.Xiaoting Huang,Siyuan Tang*.Galectin-1 ameliorates lipopolysaccharide-induced acute lung injury via AMPK-Nrf2 pathway in mice. Free Radical Biology and Medicine, 2020, 146: 222-233 (IF: 6.17)

29. Qirong Chen,Siyuan Tang*.Relationship between critical thinking disposition and research competence among clinical nurses: A cross‐sectional study, Journal of Clinical Nursing, 2020,29:1332-1340(IF:1.757)

30. Ziyao Guan, Siyuan Tang*.Postpartum depression and its correlates in middle-class women in Hunan, China. Asian Social Work and Policy Review. 2020; 00: 1-11

31. Mingjie Luo,Shanshan,Siyuan Tang*.Fasting before or after wound injury accelerates wound healing through the activation of pro-angiogenic SMOC1and SCG2. Theranostics,202002(IF: 8.579)

32. Zun Wang,Siyuan Tang*.Identification of novel functional CpG-SNPs associated with type 2 diabetes and coronary artery disease. Molecular Genetics and Genomics, 295(3):607-619. (IF: 2.79)

33. Qirong Chen,Dan Liu,Siyuan Tang*.The nurse outcomes and patient outcomes following the High‐Quality Care Project. INTERNATIONAL,202005(IF: 2.034)

34. Qirong Chen, Mei Sun, Siyuan Tang*, Postpartum depression and family function in Chinese women within 1 year after childbirth: A cross-sectional study. Research in Nursing & Health, 2021,44(4), 633–642(IF: 2.228)

35.Minhui Liu,Siyuan Tang*. Associations between symptoms of pain, insomnia and depression, and frailty in older adults: A cross-sectional analysis of a cohort study. INTERNATIONAL JOURNAL OF NURSING STUDIES,2021,117.(IF:5.837)

36. Qingzhong Hua,Siyuan Tang*.PPAR-y mediates the anti-pulmonary fibrosis effect of icaritin. TOXICOLOGY LETTERS, 2021,350,81-90. (IF:4.372)

37. Xiaoting Huang,Wei Liu,Siyuan Tang*.Activation of N-methyl-D-aspartate receptor regulates insulin sensitivity and lipid metabolism. Theranostics. Theranostics, 2021 Jan 1;11(5):2247-2262.(IF:11.556)

38. Guan, Z., Wang, Y., Hu, X., Chen, J., Qin, C., Tang, S*., & Sun, M*. Postpartum depression and family function in Chinese women within 1 year after childbirth: A cross-sectional study. Research in nursing & health, 2021, 44(4), 633–642.

39.Hua, Q., Huang, X., Xie, W., Zhao, F., Cheng, H., Luo, Z., Han, J., Wang, Z., Zeng, Q., Lin, M., Zhou, T., Zhang, J., Gu, C*., Liu, W*., & Tang, S*. PPARγ mediates the anti-pulmonary fibrosis effect of icaritin. Toxicology letters, 2021, 350, 81–90.

40.Chen, Q., Huang, C*., Castro, A. R., & Tang, S*. Instruments for measuring nursing research competence: a protocol for a scoping review. BMJ open, 2021, 11(2)

41. Zhang, H., Xu, K., Sun, Y., Xiao, L. D., Yan, F., & Tang, S*. Exercise for preventing falls in post-stroke patients: A network meta-analysis. Research in nursing & health, 2022, 45(5), 525–536.

42. Huang, X. T., Xiong, D. Y., Xiao, J. N., Deng, L., Liu, W*., & Tang, S. Y*.  Kindlin-2 protects pancreatic β cells through inhibiting NLRP3 inflammasome activation in diabetic mice. Biochemical and biophysical research communications, 2022, 614, 1–8.

43.Yan, F., Xiao, L. D*., Zhou, K., Li, Z., & Tang, S*. Perceptions and help-seeking behaviours among community-dwelling older people with urinary incontinence: A systematic integrative review. Journal of advanced nursing, 2022, 78(6), 1574–1587.

44.Zeng, Q., Zhou, T., Zhao, F., Xiong, D., He, B., Hua, Q., Lin, M., Deng, L., Sang, X., Xie, W., Chen, J., Wang, Z., Ren, L., Luo, Z., Huang, X*., Liu, W*., & Tang, S*. p62-Nrf2 Regulatory Loop Mediates the Anti-Pulmonary Fibrosis Effect of Bergenin. Antioxidants (Basel, Switzerland), 2022, 11(2), 307.(if>5)

45.Luo, R., Ji, Y., Liu, Y. H*., Sun, H., Tang, S*., & Li, X*. Relationships among social support, coping style, self-stigma, and quality of life in patients with diabetic foot ulcer: A multicentre, cross-sectional study. International wound journal, 2023, 20(3), 716–724.


专利(近5年)

(1)一次性手柄式海绵消毒刷,实用新型专利,2018年8月21日授权。

(2)一种医用消毒液恒温器,实用新型专利,2018年9月7日授权。

(3)一种肠内压测量装置,实用新型专利,2020年9月15日授权。

(4)一种新型鼻胃管、胃空肠营养管,实用新型专利,2021年9月15日授权。

(5)一种提示服药的药盒,实用新型专利,2021年12月14日授权。

(6)一种用于监测胸腔压的胃管,国家发明专利,2022年12月10日授权。

(7)一种双基因监控反应体系、试剂盒及其应用,国家发明专利,2020年10月13日授权。

(8)一种超声阵列信号通道间时延差高精度模拟装置及方法,国家发明专利,2022年4月26日授权。

(9)一种口咽通气道(韩国PCT授权通知)。国际发明专利,2021年9月24日授权。

(10)一种基于陀螺仪的机械手臂热源追踪辅助系统及其方法(美国),国际发明专利,2021年9月27日授权。


学术兼职(不超过5项)

(1)教育部高等学校护理学教育指导委员会委员

(2)教育部高等学校护理学认证工作委员会副主任委员

(3)国务院学位委员会第八届学科评议组成员、护理学组秘书长

(4)国家虚拟仿真实验教学创新联盟医学领域工作委员会副主任委员、护理学组组长

(5)国家虚拟仿真实验教学创新联盟医学领域护理学专业委员会主任委员

(6)教育部高等学校护理学类实践实训教育工作组副组长

(7)第五届全国高等学校护理学类专业教材评审委员会副主任委员

(8)全国护理学名词审定委员会副主任委员

(9)湖南省健康管理学会副会长


联系方式

tangsyuan@126.com